Isaac Barrow (1613 – 24 June 1680) was an English clergyman and Bishop, consecutively, of Sodor and Man and St Asaph, and also served as Governor of the Isle of Man. He was the founder of the Bishop Barrow Trust. During his time as Bishop of Sodor and Man and Governor of the Isle of Man, he enacted significant social, political, and ecclesiastical reforms. He is sometimes confused with his more famous namesake and nephew, Isaac Barrow (1630–1677), the mathematician and theologian.