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Isomethadone (INN, BAN; trade nameLiden; also known as isoamidone) is a synthetic opioid analgesic and antitussive related to methadone that was used formerly as a pharmaceutical drug but is now no longer marketed. Isomethadone was used as both an analgesic and antitussive. It binds to and activates both the μ- and δ-opioid receptors, with the (S)-isomer being the more potent of its two enantiomers. Isomethadone is a Schedule II controlled substance in the United States, with an ACSCN of 9226 and a 2014 aggregate manufacturing quota of 5 g. The salts in use are the hydrobromide (HBr, free base conversion ratio 0.793), hydrochloride (HCl, 0.894), and HCl monohydrate (0.850). Isomethadone is also regulated internationally as a Schedule I controlled substance under the United Nations Single C

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  • Isomethadone (en)
  • イソメサドン (ja)
  • Izometadon (pl)
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  • Izometadon – organiczny związek chemiczny, syntetyczny lek opioidowy objęty Jednolitą konwencją o środkach odurzających z 1961 roku (wykaz I). W Polsce jest w wykazie I-N Ustawy o przeciwdziałaniu narkomanii. (pl)
  • イソメサドン(Isomethadone)は、かつて調合薬として使われていたが現在はもう市販されていないメサドンと関連する合成オピオイドの鎮痛薬及び鎮咳薬である。μ-とδ-のオピオイド受容体の両方に結合して活性化する。2つのエナンチオマーのうち、(S)-異性体の方が作用が強い。イソメサドンは、アメリカ合衆国では付表IIの規制物質であり、また1961年の麻薬に関する単一条約の付表Iに掲載され、国際的にも規制されている。 (ja)
  • Isomethadone (INN, BAN; trade nameLiden; also known as isoamidone) is a synthetic opioid analgesic and antitussive related to methadone that was used formerly as a pharmaceutical drug but is now no longer marketed. Isomethadone was used as both an analgesic and antitussive. It binds to and activates both the μ- and δ-opioid receptors, with the (S)-isomer being the more potent of its two enantiomers. Isomethadone is a Schedule II controlled substance in the United States, with an ACSCN of 9226 and a 2014 aggregate manufacturing quota of 5 g. The salts in use are the hydrobromide (HBr, free base conversion ratio 0.793), hydrochloride (HCl, 0.894), and HCl monohydrate (0.850). Isomethadone is also regulated internationally as a Schedule I controlled substance under the United Nations Single C (en)
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  • None (en)
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  • Anlage II (en)
legal US
  • Schedule II (en)
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  • O=CCC2=CC=CC=C2 (en)
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