James O'Reilly, also known as Seamas O'Reilly, (1916–1992) was a nationalist politician in Ireland. O'Reilly was a farmer and an activist in the Nationalist Party and was elected to Kilkeel Rural District Council. He stood unsuccessfully for the Irish Anti-Partition League in the 1948 Armagh by-election. O'Reilly was elected in the 1958 Northern Ireland general election, representing Mourne, holding the seat until the abolition of the Parliament of Northern Ireland in 1972. He became prominent in the 1960s, when he tried to have Orange Order parades through Kilkeel rerouted.