I-351 was an I-351-class (Senho type submarine (潜補型潜水艦, Sen-Ho-gata sensuikan) tanker/transport submarine built for the Imperial Japanese Navy during World War II. Originally designed to support flying boats in forward areas, she was converted into a tanker. The only submarine of her class to be completed, she was commissioned in late January 1945 and was sunk on the return leg of her second voyage in July 1945.