John Holt (1721—1784) was a colonial American newspaper publisher, printer, postmaster, and mayor of Williamsburg, Virginia, United States. He was involved with publishing the Connecticut Gazette, the New York Gazette, and the New-York Journal newspapers. He worked with Benjamin Franklin, the prominent publisher James Parker, and Founding Father Samuel Adams. He had a store that sold miscellaneous supplies, ink, paper, and books on a variety of subjects including religion, freemasonry, economics, history, archaeology, poetry, and biographies.