The John Perkins House is a historic house museum on the grounds of the Wilson Museum at 120 Perkins Street in Castine, Maine. Built in 1765 on Court Street, it is one of the oldest houses in Castine, and a well-preserved example of Georgian architecture; it was moved to its present location in 1968-69 and restored. The house was listed on the National Register of Historic Places in 1969. It is open for tours on a limited basis during July and August; the Gallery located in the basement is open from May to September.