Karen MacKenzie (maiden name Cooper; formerly Fairgate) is a long-running fictional character in the CBS primetime soap opera Knots Landing. Karen is portrayed by actress Michele Lee, and has appeared on the show since its pilot episode, first broadcast on December 27, 1979. Knots Landing follows the trials of four middle-class families living on a suburban cul-de-sac known as Seaview Circle in California. Lee portrayed Karen for the entire run of Knots Landing, being the sole cast member to appear in every episode of its fourteen seasons. At the time, her appearances in all 344 episodes set a record for an actress on American primetime television. Karen's storylines focus on family troubles, business dealings, addiction and kidnapping.