Karen Eileen Spilka (born January 11, 1953) is an American politician and attorney serving as a Democratic member of the Massachusetts Senate. She represents the 2nd Middlesex and Norfolk district, which includes the towns of Ashland, Framingham, Franklin, Holliston, Hopkinton, Medway and Natick in the MetroWest region of Massachusetts. She has served as the 95th President of the Massachusetts Senate since July 2018. Previously she served as a member of the Massachusetts House of Representatives from 2001 to 2005.