Knoxville is an unincorporated community and census-designated place in Crawford County, Georgia, United States. It is the Crawford County seat. The community is part of the Macon Metropolitan Statistical Area. As of the 2020 census, Knoxville had a population of 65. Knoxville was founded in 1823 as seat of the newly formed Crawford County. It was incorporated as a town in 1825. The former city's municipal charter was dissolved in 1995 pursuant to a Georgia law which abolished city governments which were defunct or minimally operative.