Konomi Takeishi (武石 この実, Takeishi Konomi, born 9 October 1991 in Aizuwakamatsu) is a Japanese sprinter who specialises in the 400 metres. She won the bronze medal in the women's 4 × 400 metres relay and mixed 4 × 400 metres relay at the 2019 Asian Championships. She also competed in the women's 4 × 400 metres relay at the 2019 World Relays. She is the former Japanese best record holder in the Mixed 4 × 400 metres relay (3:23.83 minutes).