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Co-solvents (in water solvent) are defined as kosmotropic (order-making) if they contribute to the stability and structure of water-water interactions. In contrast, chaotropic (disorder-making) agents have the opposite effect, disrupting water structure, increasing the solubility of nonpolar solvent particles, and destabilizing solute aggregates. Kosmotropes cause water molecules to favorably interact, which in effect stabilizes intramolecular interactions in macromolecules such as proteins.

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  • Cosmotropico (it)
  • Kosmotropic (en)
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  • Co-solvents (in water solvent) are defined as kosmotropic (order-making) if they contribute to the stability and structure of water-water interactions. In contrast, chaotropic (disorder-making) agents have the opposite effect, disrupting water structure, increasing the solubility of nonpolar solvent particles, and destabilizing solute aggregates. Kosmotropes cause water molecules to favorably interact, which in effect stabilizes intramolecular interactions in macromolecules such as proteins. (en)
  • I co-solventi (in solvente acquoso) sono definiti cosmotropici (dal greco "che fanno ordine") qualora contribuiscano alla stabilità e alla struttura delle interazioni acqua-acqua. I cosmotropi favoriscono l'interazione tra molecole d'acqua. il che stabilizza anche le interazioni intramolecolari in macromolecole come le proteine. Qualora il co-solvente causasse l'effetto opposto, prenderebbe il nome di agente caotropico ("che fanno disordine), il quale disturba la struttura dell'acqua favorendo, così, la solubilità di particelle non polari e destabilizzando gli aggregati di soluto. (it)
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  • Co-solvents (in water solvent) are defined as kosmotropic (order-making) if they contribute to the stability and structure of water-water interactions. In contrast, chaotropic (disorder-making) agents have the opposite effect, disrupting water structure, increasing the solubility of nonpolar solvent particles, and destabilizing solute aggregates. Kosmotropes cause water molecules to favorably interact, which in effect stabilizes intramolecular interactions in macromolecules such as proteins. (en)
  • I co-solventi (in solvente acquoso) sono definiti cosmotropici (dal greco "che fanno ordine") qualora contribuiscano alla stabilità e alla struttura delle interazioni acqua-acqua. I cosmotropi favoriscono l'interazione tra molecole d'acqua. il che stabilizza anche le interazioni intramolecolari in macromolecole come le proteine. Qualora il co-solvente causasse l'effetto opposto, prenderebbe il nome di agente caotropico ("che fanno disordine), il quale disturba la struttura dell'acqua favorendo, così, la solubilità di particelle non polari e destabilizzando gli aggregati di soluto. (it)
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