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Kyrle disease is identified as a form of an acquired perforating disease. Other major perforating diseases are elastosis perforans serpiginosa and reactive perforating collagenosis. Recently, however, there is a controversy on categorizing Kyrle disease with perforating dermatosis or a subtype of acquired perforating collagenosis.

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  • Kyrle disease (en)
  • Болезнь Кирле (ru)
rdfs:comment
  • Болезнь Кирле — редкое заболевание кожи, которое проявляется нарушением кератинизации и проникновением ороговевших клеток в дерму. Впервые заболевание описал в 1916 году австрийский дерматолог и патоморфолог Йозеф Кирле. (ru)
  • Kyrle disease is identified as a form of an acquired perforating disease. Other major perforating diseases are elastosis perforans serpiginosa and reactive perforating collagenosis. Recently, however, there is a controversy on categorizing Kyrle disease with perforating dermatosis or a subtype of acquired perforating collagenosis. (en)
foaf:name
  • Kyrle disease (en)
name
  • Kyrle disease (en)
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DiseasesDB
ICD
  • L87.0 (en)
synonyms
  • Hyperkeratosis follicularis et parafollicularis in cutem penetrans (en)
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  • Kyrle disease is identified as a form of an acquired perforating disease. Other major perforating diseases are elastosis perforans serpiginosa and reactive perforating collagenosis. Recently, however, there is a controversy on categorizing Kyrle disease with perforating dermatosis or a subtype of acquired perforating collagenosis. Kyrle disease was first described by Josef Kyrle in 1916 when a diabetic woman presented generalized hyperkeratotic nodules. The disease is distinguished by large papules with central keratin plug on the skin, usually on the legs of the patient and is often in conjunction with liver, kidney or diabetic disorders. It can affect both females and males with a 6:1 ratio. The papules usually show up on the patient with an average age of 30 years. Kyrle disease is a rare disease unless there is a high count of patients with chronic kidney failure. The disease seems to be more prevalent in African Americans, which can be correlated to the high incidence of diabetes mellitus and kidney failure in the population. (en)
  • Болезнь Кирле — редкое заболевание кожи, которое проявляется нарушением кератинизации и проникновением ороговевших клеток в дерму. Впервые заболевание описал в 1916 году австрийский дерматолог и патоморфолог Йозеф Кирле. (ru)
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DiseasesDB
  • 32593
ICD10
  • (ILDSL87.000)
  • L87.0
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