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LY-88329 is an opioid receptor ligand related to medicines such as pethidine. It has high affinity to the μ-opioid receptor, but unlike structurally related drugs such as 3-methylfentanyl and OPPPP, LY-88329 is a potent opioid antagonist. In animal studies it blocks the effects of morphine and has anorectic action.

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  • LY-88329 (en)
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  • LY-88329 is an opioid receptor ligand related to medicines such as pethidine. It has high affinity to the μ-opioid receptor, but unlike structurally related drugs such as 3-methylfentanyl and OPPPP, LY-88329 is a potent opioid antagonist. In animal studies it blocks the effects of morphine and has anorectic action. (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/LY88329_structure.png
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SMILES
  • C[C@H]1CNCCCC3=CC=CC=C3 (en)
StdInChI
StdInChIKey
  • IQGJBVSSFDCTAJ-HTAPYJJXSA-N (en)
has abstract
  • LY-88329 is an opioid receptor ligand related to medicines such as pethidine. It has high affinity to the μ-opioid receptor, but unlike structurally related drugs such as 3-methylfentanyl and OPPPP, LY-88329 is a potent opioid antagonist. In animal studies it blocks the effects of morphine and has anorectic action. (en)
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CAS number
  • 78693-86-4
ChEMBL
  • 94345
PubChem
  • 10042707
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