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Lactocillin is a thiopeptide antibiotic which is encoded for and produced by biosynthetic genes clusters in the bacteria Lactobacillus gasseri. Lactocillin was discovered and purified in 2014. Lactobacillus gasseri is one of the four Lactobacillus bacteria found to be most common in the human vaginal microbiome. Due to increasing levels of pathogenic resistance to known antibiotics, novel antibiotics are increasingly valuable. Lactocillin could function as a new antibiotic that could help people fight off infections that are resistant to many other antibiotics.

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  • Lactocillin (en)
  • ラクトシリン (ja)
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  • Lactocillin is a thiopeptide antibiotic which is encoded for and produced by biosynthetic genes clusters in the bacteria Lactobacillus gasseri. Lactocillin was discovered and purified in 2014. Lactobacillus gasseri is one of the four Lactobacillus bacteria found to be most common in the human vaginal microbiome. Due to increasing levels of pathogenic resistance to known antibiotics, novel antibiotics are increasingly valuable. Lactocillin could function as a new antibiotic that could help people fight off infections that are resistant to many other antibiotics. (en)
  • ラクトシリン(Lactocillin)は、チオペプチドの 抗生物質である。ラクトシリンは、ガセリ菌(Lactobacillus gasseri)によって産生される。 (ja)
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  • Lactocillin.svg (en)
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  • N-alanin (en)
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  • Lactocillin is a thiopeptide antibiotic which is encoded for and produced by biosynthetic genes clusters in the bacteria Lactobacillus gasseri. Lactocillin was discovered and purified in 2014. Lactobacillus gasseri is one of the four Lactobacillus bacteria found to be most common in the human vaginal microbiome. Due to increasing levels of pathogenic resistance to known antibiotics, novel antibiotics are increasingly valuable. Lactocillin could function as a new antibiotic that could help people fight off infections that are resistant to many other antibiotics. (en)
  • ラクトシリン(Lactocillin)は、チオペプチドの 抗生物質である。ラクトシリンは、ガセリ菌(Lactobacillus gasseri)によって産生される。 (ja)
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IUPAC name
  • N-({2'-[(26Z)-26-Ethyliden-19,29-bis(1-hydroxyethyl)-12-{[(1H-indol-3-ylcarbonyl)sulfanyl]methyl}-14,21,28,31-tetraoxo-10,17,24,34-tetrathia-6,13,20,27,30,35,36,37,38-nonaazahexacyclo[30.2.1.18,11.1]15,18.122,25.02,7]octatriaconta-1(35),2,4,6,8,11(38),18(37),22,25(36),32-decaen-5-yl]-2,4'-bi-1,3-thiazol-4-yl}carbonyl)alanin (en)
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