About: Lefty (protein)     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:ProteinMolecule, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)
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Lefty (left-right determination factors) are a class of proteins that are closely related members of the TGF-beta superfamily of growth factors. These proteins are secreted and play a role in left-right asymmetry determination of organ systems during development. Mutations of the genes encoding these proteins have been associated with left-right axis malformations, particularly in the heart and lungs.

AttributesValues
rdf:type
rdfs:label
  • Lefty (proteína) (es)
  • Lefty (protein) (en)
rdfs:comment
  • Los factores de determinación izquierda-derecha (Lefty) son proteínas que están estrechamente relacionadas con miembros de la familia de los factores de crecimiento TGF-beta. Estas proteínas son secretadas y juegan un papel en la determinación de la asimetría bilateral de los órganos durante el desarrollo embrionario.​Mutaciones en los genes que codifican estas proteínas están asociados con malformaciones en el crecimiento asimétrico de los órganos, particularmente corazón y pulmones.​ (es)
  • Lefty (left-right determination factors) are a class of proteins that are closely related members of the TGF-beta superfamily of growth factors. These proteins are secreted and play a role in left-right asymmetry determination of organ systems during development. Mutations of the genes encoding these proteins have been associated with left-right axis malformations, particularly in the heart and lungs. (en)
foaf:name
  • left-right determination factor 2 (en)
  • left-right determination factor 1 (en)
name
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/Leftynodaldiagram.jpg
dcterms:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
sameAs
dbp:wikiPageUsesTemplate
thumbnail
OMIM
AltSymbols
  • LEFTB (en)
  • TGFB4, EBAF (en)
symbol
UniProt
  • O00292 (en)
  • O75610 (en)
has abstract
  • Los factores de determinación izquierda-derecha (Lefty) son proteínas que están estrechamente relacionadas con miembros de la familia de los factores de crecimiento TGF-beta. Estas proteínas son secretadas y juegan un papel en la determinación de la asimetría bilateral de los órganos durante el desarrollo embrionario.​Mutaciones en los genes que codifican estas proteínas están asociados con malformaciones en el crecimiento asimétrico de los órganos, particularmente corazón y pulmones.​ (es)
  • Lefty (left-right determination factors) are a class of proteins that are closely related members of the TGF-beta superfamily of growth factors. These proteins are secreted and play a role in left-right asymmetry determination of organ systems during development. Mutations of the genes encoding these proteins have been associated with left-right axis malformations, particularly in the heart and lungs. (en)
Arm
  • q (en)
band
Chromosome
EntrezGene
HGNCid
RefSeq
  • NM_003240 (en)
  • NM_020997 (en)
arm
  • q
band
  • 42.1
chromosome
  • 1
EntrezGene
  • 10637
  • 7044
HGNCid
  • 3122
  • 6552
RefSeq
  • NM_003240
  • NM_020997
UniProt
  • O00292
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