Leishmania mexicana belongs to the Leishmania genus and is the causal agent of cutaneous leishmaniasis in Mexico and central America. Leishmania mexicana is an obligate intracellular protozoan parasite that causes the cutaneous form of leishmaniasis. This species of Leishmania is found in America. The infection with L. mexicana occurs when an individual is bitten by an infected sandfly that injects infective promastigotes, which are carried in the salivary glands and expulsed by the proboscis, directly to the skin.
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| - Leishmania mexicana (es)
- Leishmania mexicana (en)
- Leishmania mexicana (pt)
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| - Leishmania mexicana é uma espécie de protozoário flagelado da família Trypanosomatidae. A espécie é o agente etiológico da leishmaniose cutânea do Novo Mundo. A espécie foi descrita em 1953 por Biagi como Leishmania tropica mexicana. Em 1962, Garnham emendou a descrição considerando-a uma espécie distinta. (pt)
- Leishmania mexicana pertenece al género Leishmania. Es el agente causal de la leishmaniasis cutánea en México y América Central. La parasitosis se considera endémica en grandes áreas tropicales y subtropicales. Leishmania mexicana es un protozoario parásito intracelular obligado que causa la forma cutánea de la leishmaniasis. El tratamiento de la leishmaniasis causada por L. mexicana consiste en antimoniales pentavalentes como pentostam o inyectados directamente en la úlcera o intramuscularmente. (es)
- Leishmania mexicana belongs to the Leishmania genus and is the causal agent of cutaneous leishmaniasis in Mexico and central America. Leishmania mexicana is an obligate intracellular protozoan parasite that causes the cutaneous form of leishmaniasis. This species of Leishmania is found in America. The infection with L. mexicana occurs when an individual is bitten by an infected sandfly that injects infective promastigotes, which are carried in the salivary glands and expulsed by the proboscis, directly to the skin. (en)
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| - Biagi, 1953, emend. Garnham, 1962 (en)
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| - Leishmania mexicana in a biopsy specimen from a skin lesion stained with H&E. The amastigotes are lining the walls of two vacuoles, a typical arrangement. The species identification was derived from culture followed by isoenzyme analysis. (en)
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| - Leishmania mexicana belongs to the Leishmania genus and is the causal agent of cutaneous leishmaniasis in Mexico and central America. Leishmania mexicana is an obligate intracellular protozoan parasite that causes the cutaneous form of leishmaniasis. This species of Leishmania is found in America. The infection with L. mexicana occurs when an individual is bitten by an infected sandfly that injects infective promastigotes, which are carried in the salivary glands and expulsed by the proboscis, directly to the skin. The life cycle of this and other Leishmania species begin when an infected Phlebotomine bites and injects promastigotes in the skin of the mammal host. Those promastigotes are engulfed by phagocytic cells, as macrophages and dendritic cells. The parasites are kept inside in a parasitophorous vacuole, then they will transform to amastigotes and divide until brock the cell membrane. They are released to infect new cells as amastigotes stage. When an uninfected sand fly bites an infected mammal reservoir, the sandfly ingests the amastigotes, therefore they transform in promastigotes and divide in the midgut of the fly, those promastigotes migrates to the proboscis and are able to produce Leishmaniasis disease. There are no blood stages in the life cycle of L. mexicana (unlike Malaria and Trypanosomiasis). Leishmania mexicana can induce the cutaneous and diffuse cutaneous clinical manifestations in humans. The cutaneous type develops an ulcer at the bite site, here the amastigotes do not spread and the ulcers become visible either a few days or several months after the initial bite. The diffuse cutaneous type begins when the amastigote diffuses through the skin and metastasize to other tissue. This type does not produce ulcers and there is no treatment. Treatment of Leishmaniasis caused by L. mexicana consists on pentavalent antimonials as Pentostam or Glucantime injected direct into the ulcer or Intramuscular. Prevention of L. mexicana infection is principally avoiding the bite of the infected sandfly. (en)
- Leishmania mexicana pertenece al género Leishmania. Es el agente causal de la leishmaniasis cutánea en México y América Central. La parasitosis se considera endémica en grandes áreas tropicales y subtropicales. Leishmania mexicana es un protozoario parásito intracelular obligado que causa la forma cutánea de la leishmaniasis. Esta especie de Leishmania se encuentra en América. La infección con L. mexicana ocurre cuando un individuo es picado por un flebótomo infectado que inyecta promastigotos infecciosos, los que son transportados en las glándulas salivales y expulsados por la proboscis, directamente a la piel. El ciclo de vida de esta y otras especies de Leishmania comienza cuando un flebótomo infectado pica e inyecta promastigotos en la piel del huésped mamífero. Esos promastigotos son englobados por células fagocíticas, como macrófagos y células dendríticas. Los parásitos se mantienen dentro de una vacuola parasitófora, luego se transforman en amastigotos y se dividen hasta formar una membrana celular. Se liberan para infectar nuevas células en estadio de amastigotos. Cuando una mosca flebótomo no infectada pica a un mamífero infectado adquiere los amastigotos, que por lo tanto se transforman en promastigotos y se dividen en el interior de la mosca, esos promastigotos migran a la probóscide y pueden producir la enfermedad de leishmaniasis. No hay etapas sanguíneas en el ciclo de vida de L. mexicana (a diferencia de la malaria y la tripanosomiasis). L. mexicana puede inducir manifestaciones cutáneas y cutáneas difusas en humanos. El tipo cutáneo desarrolla una úlcera en el sitio de la mordida, aquí los amastigotos no se propagan y las úlceras se vuelven visibles ya sea unos pocos días o varios meses después de la mordida inicial. El tipo cutáneo difuso comienza cuando el amastigote se difunde a través de la piel y se metastatiza a otro tejido. Este tipo no produce úlceras y no hay tratamiento. El tratamiento de la leishmaniasis causada por L. mexicana consiste en antimoniales pentavalentes como pentostam o inyectados directamente en la úlcera o intramuscularmente. La prevención de la infección por L. mexicana consiste principalmente en evitar la picadura de mosquitas flebótomos. (es)
- Leishmania mexicana é uma espécie de protozoário flagelado da família Trypanosomatidae. A espécie é o agente etiológico da leishmaniose cutânea do Novo Mundo. A espécie foi descrita em 1953 por Biagi como Leishmania tropica mexicana. Em 1962, Garnham emendou a descrição considerando-a uma espécie distinta. (pt)
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