Leonardo V Tocco (1591 – 24 January 1641) was the titular Despot of Epirus and Count Palatine of Cephalonia and Zakynthos from the death of his father Francesco Tocco in 1596 to his own death in 1641. In addition to holding titular claims to lordships in Greece, Leonardo was also the lord of Refrancore in Montferrat, Italy, as well as Apice and , which he purchased in 1639. Upon Leonardo's death, his claims and titles were inherited by his son, Antonio Tocco.