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In enzymology, a leukotriene-B4 20-monooxygenase (EC 1.14.13.30) is an enzyme that catalyzes the chemical reaction (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H+ + O2 (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14- tetraenoate + NADP+ + H2O The 4 substrates of this enzyme are , NADPH, H+, and O2, whereas its 4 products are , , NADP+, and H2O.

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  • Leucotriene-B4 20-monoossigenasi (it)
  • Leukotriene-B4 20-monooxygenase (en)
  • ロイコトリエンB4-20-モノオキシゲナーゼ (ja)
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  • ロイコトリエンB4-20-モノオキシゲナーゼ（leukotriene-B4 20-monooxygenase）は、アラキドン酸代謝酵素の一つで、次の化学反応を触媒する酸化還元酵素である この酵素の基質はロイコトリエンB4、NADPH、H+とO2で、生成物は20-OH-ロイコトリエン、NADP+とH2Oである。補因子としてヘムを用いる。 組織名は(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating) で、別名にleukotriene-B4 20-hydroxylase、leucotriene-B4 ω-hydroxylase、LTB4 20-hydroxylase、LTB4 ω-hydroxylaseがある。 (ja)
  • La leucotriene-B4 20-monoossigenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: (6Z,8E,10E,14Z)-(5S,12R)-5,12-diidrossiicosa-6,8,10,14-tetra + NADPH + H+ + O2 ⇄ (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-triidrossiicosa-6,8,10,14-tetraenoato + NADP+ + H2O L'enzima è una proteina eme-tiolata (P-450). Non è uguale alla leucotriene-E4 20-monoossigenasi (numero EC 1.14.13.34). (it)
  • In enzymology, a leukotriene-B4 20-monooxygenase (EC 1.14.13.30) is an enzyme that catalyzes the chemical reaction (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H+ + O2 (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14- tetraenoate + NADP+ + H2O The 4 substrates of this enzyme are , NADPH, H+, and O2, whereas its 4 products are , , NADP+, and H2O. (en)
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  • leukotriene-B4 20-monooxygenase (en)
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  • leukotriene-B4 20-monooxygenase (en)
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  • In enzymology, a leukotriene-B4 20-monooxygenase (EC 1.14.13.30) is an enzyme that catalyzes the chemical reaction (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H+ + O2 (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14- tetraenoate + NADP+ + H2O The 4 substrates of this enzyme are , NADPH, H+, and O2, whereas its 4 products are , , NADP+, and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,N ADPH:oxygen oxidoreductase (20-hydroxylating). Other names in common use include leukotriene-B4 20-hydroxylase, leucotriene-B4 omega-hydroxylase, LTB4 20-hydroxylase, and LTB4 omega-hydroxylase. This enzyme participates in arachidonic acid metabolism. It employs one cofactor, heme. (en)
  • ロイコトリエンB4-20-モノオキシゲナーゼ（leukotriene-B4 20-monooxygenase）は、アラキドン酸代謝酵素の一つで、次の化学反応を触媒する酸化還元酵素である この酵素の基質はロイコトリエンB4、NADPH、H+とO2で、生成物は20-OH-ロイコトリエン、NADP+とH2Oである。補因子としてヘムを用いる。 組織名は(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating) で、別名にleukotriene-B4 20-hydroxylase、leucotriene-B4 ω-hydroxylase、LTB4 20-hydroxylase、LTB4 ω-hydroxylaseがある。 (ja)
  • La leucotriene-B4 20-monoossigenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: (6Z,8E,10E,14Z)-(5S,12R)-5,12-diidrossiicosa-6,8,10,14-tetra + NADPH + H+ + O2 ⇄ (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-triidrossiicosa-6,8,10,14-tetraenoato + NADP+ + H2O L'enzima è una proteina eme-tiolata (P-450). Non è uguale alla leucotriene-E4 20-monoossigenasi (numero EC 1.14.13.34). (it)
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  • 1.14.13.30
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