The Little Seboeis River is a short stream in Maine Township 4, Range 7, WELS, Penobscot County, Maine. From its source (45°59′09″N 68°34′35″W / 45.9858°N 68.5765°W), the river runs 5.5 miles (8.9 km) south and west to its confluence with the Seboeis River.