Lorenzo Panepinto (Italian pronunciation: [loˈrɛntso paneˈpinto]; January 4, 1865 – May 16, 1911) was an Italian politician and teacher. He was the founder of the Fascio dei lavoratori (Workers League) in his hometown Santo Stefano Quisquina, editor of the newspaper La Plebe and member of the Comitato della Federazione Regionale Socialista. He was killed by the Sicilian Mafia.