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Lundh's test is a test of function of the exocrine function of the pancreas gland. The exocrine role of the pancreas involves release of various digestive enzymes, including lipase and proteases, such as trypsin, in response to hormonal stimulation after eating. Disorders of the pancreas including chronic pancreatitis, cystic fibrosis and pancreatic cancer can lead to decreased pancreatic exocrine activity. A positive Lundh's test is indicative of decreased exocrine function of the pancreas, but theoretically may be positive if there is lack of release of cholecystokinin.

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  • اختبار لوند (ar)
  • Lundh's test (en)
  • Teste de Lundh (pt)
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  • اختبار لوند (بالإنجليزية: Lundh's test)‏ هو اختبار لوظيفة إفرازات غدة البنكرياس. يتضمن الدور الخارجي للبنكرياس إفراز العديد من إنزيمات الجهاز الهضمي، بما في ذلك الليباز والبروتياز، مثل التربسين، استجابةً للتحفيز الهرموني بعد الأكل. يمكن أن تؤدي اضطرابات البنكرياس بما في ذلك التهاب البنكرياس المزمن والتليف الكيسي وسرطان البنكرياس إلى انخفاض نشاط إفرازات البنكرياس. يشير اختبار لوند الإيجابي إلى انخفاض وظيفة إفرازات البنكرياس الخارجية، ولكن من الناحية النظرية قد يكون إيجابيًا إذا كان هناك نقص في إطلاق الكوليسيستوكينين. (ar)
  • Lundh's test is a test of function of the exocrine function of the pancreas gland. The exocrine role of the pancreas involves release of various digestive enzymes, including lipase and proteases, such as trypsin, in response to hormonal stimulation after eating. Disorders of the pancreas including chronic pancreatitis, cystic fibrosis and pancreatic cancer can lead to decreased pancreatic exocrine activity. A positive Lundh's test is indicative of decreased exocrine function of the pancreas, but theoretically may be positive if there is lack of release of cholecystokinin. (en)
  • O teste de Lundh é um teste de função da função exócrina da glândula pâncreas, usado quando um doente tem esteatose e se suspeita de pancreatite crónica com falência pancreática. O papel exócrino do pâncreas envolve a libertação de várias enzimas digestivas, incluindo lipase e proteases, como a tripsina, em resposta à estimulação hormonal após a ingestão. Distúrbios do pâncreas, incluindo pancreatite crônica, fibrose cística e cancro pancreático podem levar à diminuição da atividade exócrina pancreática. (pt)
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  • Lundh's test (en)
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  • Contents of the duodenum (en)
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  • Determining pancreas function (en)
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  • اختبار لوند (بالإنجليزية: Lundh's test)‏ هو اختبار لوظيفة إفرازات غدة البنكرياس. يتضمن الدور الخارجي للبنكرياس إفراز العديد من إنزيمات الجهاز الهضمي، بما في ذلك الليباز والبروتياز، مثل التربسين، استجابةً للتحفيز الهرموني بعد الأكل. يمكن أن تؤدي اضطرابات البنكرياس بما في ذلك التهاب البنكرياس المزمن والتليف الكيسي وسرطان البنكرياس إلى انخفاض نشاط إفرازات البنكرياس. يتضمن اختبار لوند وضع أنبوب مع قنوات متعددة في الاثنا عشر. يحتوي هذا الأنبوب على ثقوب في المعدة وفي الاثنا عشر. يتم حقن المعدة المكونة من البروتينات والكربوهيدرات والدهون. عادةً ما يتم إعطاء دواء منشط للحركة مثل ميتوكلوبراميد لتسريع مرور الطعام إلى الإثني عشر. يتم أخذ عينة من عصير الاثنا عشر عند علامة 30 دقيقة، ثم كل 30 دقيقة حتى علامة الساعتين. يتم قياس نشاط التربسين ومتوسطه بين المجموعات الأربع. يتم تحديد الاختبار الإيجابي من خلال نشاط التربسين المنخفض في متوسط العينات، ويوحي بانخفاض وظيفة إفرازات البنكرياس. يشير اختبار لوند الإيجابي إلى انخفاض وظيفة إفرازات البنكرياس الخارجية، ولكن من الناحية النظرية قد يكون إيجابيًا إذا كان هناك نقص في إطلاق الكوليسيستوكينين. (ar)
  • Lundh's test is a test of function of the exocrine function of the pancreas gland. The exocrine role of the pancreas involves release of various digestive enzymes, including lipase and proteases, such as trypsin, in response to hormonal stimulation after eating. Disorders of the pancreas including chronic pancreatitis, cystic fibrosis and pancreatic cancer can lead to decreased pancreatic exocrine activity. Lundh's test involves placing a tube with multiple channels in to the duodenum. This tube has holes in the stomach and in the duodenum. A meal consisting of proteins, carbohydrates and fats is injected into the stomach. Typically a prokinetic medication such as metoclopramide is administered to accelerate passage of the food into the duodenum. A sample of the duodenal juice is taken at the 30 minute mark, and then every 30 minutes until the two hour mark. The activity of trypsin is measured and averaged among the 4 collections. A positive test is defined by low trypsin activity on the average of the samples, and is suggestive of decreased exocrine function of the pancreas. A positive Lundh's test is indicative of decreased exocrine function of the pancreas, but theoretically may be positive if there is lack of release of cholecystokinin. (en)
  • O teste de Lundh é um teste de função da função exócrina da glândula pâncreas, usado quando um doente tem esteatose e se suspeita de pancreatite crónica com falência pancreática. O papel exócrino do pâncreas envolve a libertação de várias enzimas digestivas, incluindo lipase e proteases, como a tripsina, em resposta à estimulação hormonal após a ingestão. Distúrbios do pâncreas, incluindo pancreatite crônica, fibrose cística e cancro pancreático podem levar à diminuição da atividade exócrina pancreática. O teste de Lundh envolve colocar um tubo com múltiplos canais no duodeno. Este tubo tem buracos no estômago e no duodeno. Uma refeição composta de proteínas, glícidos e gorduras é injetada no estômago. Tipicamente usa-se um pró-cinético como a metoclopramida para acelerar o processo. Uma amostra do suco duodenal é tirada aos 30 minutos e depois a cada 30 minutos até às duas horas. A atividade medida é essencialmente a da tripsina. Um teste positivo é definido pela baixa atividade de tripsina na média das amostras e é sugestivo de diminuição da função exócrina do pâncreas. Um teste de Lundh positivo é indicativo de diminuição da função exócrina do pâncreas, mas teoricamente pode ser positivo se houver falta de liberação de colecistocinina. (pt)
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