MIA PaCa-2 is a human pancreatic cancer cell line used extensively in pancreatic cancer research and therapy development. In 1977, MIA PaCa-2 cells were derived from the carcinoma of a 65-year-old male. The cells exhibit CK5.6, AE1/AE3, E-cadherin, vimentin, chromogranin A, synaptophysin, SSTR2, and NTR1, but not CD56. The cells have a round, epithelial morphology, and are adherent in cell culture.
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| - MIA PaCa-2 (en)
- MIA PaCa-2細胞 (zh)
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| - MIA PaCa-2是一種具有低分化能力的二倍體人類胰腺癌細胞系,在1977年取自於一名65歲男性胰腺癌患者。 MIA PaCa-2細胞會表達、AE1 / AE3、、波形蛋白、、突觸素、和,但是不會表達神經元黏附分子。細胞具有圓形的上皮形態,並且粘附在細胞培養物中。 MIA PaCa-2細胞一直作為胰腺癌的模型,廣泛應用於胰腺癌的研究和治療,對MIA PaCa-2的生理學研究有助於闡明胰腺癌的致癌機制,並且開發依靠量子點增強藥物釋放的方法。 (zh)
- MIA PaCa-2 is a human pancreatic cancer cell line used extensively in pancreatic cancer research and therapy development. In 1977, MIA PaCa-2 cells were derived from the carcinoma of a 65-year-old male. The cells exhibit CK5.6, AE1/AE3, E-cadherin, vimentin, chromogranin A, synaptophysin, SSTR2, and NTR1, but not CD56. The cells have a round, epithelial morphology, and are adherent in cell culture. (en)
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| - MIA PaCa-2 is a human pancreatic cancer cell line used extensively in pancreatic cancer research and therapy development. In 1977, MIA PaCa-2 cells were derived from the carcinoma of a 65-year-old male. The cells exhibit CK5.6, AE1/AE3, E-cadherin, vimentin, chromogranin A, synaptophysin, SSTR2, and NTR1, but not CD56. The cells have a round, epithelial morphology, and are adherent in cell culture. MIA PaCa-2 has served for decades as a model of pancreatic cancer, and studies of MIA PaCa-2 physiology have helped clarify the mechanisms of carcinogenesis in pancreatic cancer, aid the development of cancer cell lysates targeting IgG production, and augmented drug-delivery methods relying on quantum dots. (en)
- MIA PaCa-2是一種具有低分化能力的二倍體人類胰腺癌細胞系,在1977年取自於一名65歲男性胰腺癌患者。 MIA PaCa-2細胞會表達、AE1 / AE3、、波形蛋白、、突觸素、和,但是不會表達神經元黏附分子。細胞具有圓形的上皮形態,並且粘附在細胞培養物中。 MIA PaCa-2細胞一直作為胰腺癌的模型,廣泛應用於胰腺癌的研究和治療,對MIA PaCa-2的生理學研究有助於闡明胰腺癌的致癌機制,並且開發依靠量子點增強藥物釋放的方法。 (zh)
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