About: Major sperm protein

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Major sperm protein (MSP) is a nematode specific small protein of 126 amino acids with a molecular weight of 14 kDa. It is the key player in the motility machinery of nematodes that propels the crawling movement/motility of nematode sperm. It is the most abundant protein present in nematode sperm, comprising 15% of the total protein and more than 40% of the soluble protein. MSP is exclusively synthesized in spermatocytes of the nematodes. The MSP has two main functions in the reproduction of the helminthes: i) as cytosolic component it is responsible for the crawling movement of the mature sperm (without flagellum), and ii) once released, it acts as hormone on the female germ cells, where it triggers oocyte maturation and stimulates the oviduct wall to contract to bring the oocytes into po

Attributes	Values
rdf:type	Thing Biomolecule Biomolecule Protein protein
rdfs:label	Major sperm protein (en)
rdfs:comment	Major sperm protein (MSP) is a nematode specific small protein of 126 amino acids with a molecular weight of 14 kDa. It is the key player in the motility machinery of nematodes that propels the crawling movement/motility of nematode sperm. It is the most abundant protein present in nematode sperm, comprising 15% of the total protein and more than 40% of the soluble protein. MSP is exclusively synthesized in spermatocytes of the nematodes. The MSP has two main functions in the reproduction of the helminthes: i) as cytosolic component it is responsible for the crawling movement of the mature sperm (without flagellum), and ii) once released, it acts as hormone on the female germ cells, where it triggers oocyte maturation and stimulates the oviduct wall to contract to bring the oocytes into po (en)
name	Major sperm protein (en) MSP domain (en)
foaf:depiction
dcterms:subject	Cytoskeleton
Wikipage page ID	4586933 (xsd:integer)
Wikipage revision ID	1118393021 (xsd:integer)
Link from a Wikipage to another Wikipage	Caenorhabditis elegans Pseudopod Plasma membrane Metaphase Oocyte Synaptobrevin Hydrogen bond Cytoskeleton Neurotransmitter KDa NMR spectroscopy Oocytes Cis-proline Monomers Myosin Aplysia californica Hormone Substrate (biology) Actin Cytoskeleton Tyrosine kinases Ovulation Adenosine triphosphate Amino acids Fertilization Fibers Cell membrane Dimer (chemistry) Protein filament Protein Reproduction Chaperonin Cofactor (biochemistry) Ascaris suum Sperm Spermatozoon Hydrophobic Nematode X-ray crystallography Salt bridge Oviduct Tubulin Limbless locomotion Spermatocytes N-terminus Molecular weight Phosphoprotein Pilus Spermatheca Meiosis I Spermatogenesis Molecular structures Vesicle fusion Eph receptor Protein-tyrosine kinase SNARE Helminthes MAPK Immunoglobulin fold Myoepithelial Sequence identity Β sheets
sameAs	Major sperm protein Major sperm protein Major sperm protein
dbp:wikiPageUsesTemplate	dbt:Infobox_nonhuman_protein dbt:Reflist dbt:Cytoskeletal_Proteins dbt:Pfam_box
thumbnail	wiki-commons:Special:FilePath/MSPdimer.png?width=300
PROSITE	PS50202 (en)
caption	Structure of MSP dimer from A. suum. The β-sheets are shown in orange (en)
InterPro	IPR000535 (en)
Organism	C. elegans (en)
Pfam	PF00635 (en)
symbol	MSP_dom (en) msp-19 (en)
UniProt	P53017 (en)
has abstract	Major sperm protein (MSP) is a nematode specific small protein of 126 amino acids with a molecular weight of 14 kDa. It is the key player in the motility machinery of nematodes that propels the crawling movement/motility of nematode sperm. It is the most abundant protein present in nematode sperm, comprising 15% of the total protein and more than 40% of the soluble protein. MSP is exclusively synthesized in spermatocytes of the nematodes. The MSP has two main functions in the reproduction of the helminthes: i) as cytosolic component it is responsible for the crawling movement of the mature sperm (without flagellum), and ii) once released, it acts as hormone on the female germ cells, where it triggers oocyte maturation and stimulates the oviduct wall to contract to bring the oocytes into position for fertilization. MSP has first been identified in Caenorhabditis elegans. (en)
CATH	1 (xsd:integer)
EntrezGene	173981 (xsd:integer)
PDB	1 (xsd:integer)
gold:hypernym	Protein
prov:wasDerivedFrom	wikipedia-en:Major_sperm_protein?oldid=1118393021&ns=0
page length (characters) of wiki page	18899 (xsd:nonNegativeInteger)
Symbol	MSP_dom
foaf:isPrimaryTopicOf	wikipedia-en:Major_sperm_protein

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