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Malcolm K. Brenner (born August 4, 1951, in the UK) is a British clinical scientist working mostly in the field of gene therapy and immunotherapy applied to malignancy. In 2016, Dr. Brenner was elected to the National Academy of Medicine, part of the National Academies of Sciences, Engineering, and Medicine. The move in 1994 reflected his growing interest in the genetic-modification of T-cells for cancer therapy, cancer vaccines and monoclonal antibodies.

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  • مالكوم برينر (ar)
  • Malcolm Brenner (es)
  • Malcolm Brenner (en)
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  • مالكوم برينر (بالإنجليزية: Malcolm Brenner)‏ هو عالم مناعة بريطاني، ولد في 4 أغسطس 1951. (ar)
  • Malcolm K. Brenner (4 de agosto de 1951 (71 años) es un científico clínico británico que trabaja mayoritariamente en el campo de terapia génica y la inmunoterapia aplicada a malignidad. Se educó en el Forest School London y luego en el Emmanuel College, de la Universidad de Cambridge. Recibió su grado médico y subsiguiente Ph.D. de la Universidad de Cambridge, Inglaterra. En los 1980s, fue un conferenciante en Hematología en Hospital Libre Real en Londres. En 1990, dejó el Reino Unido para trabajar en el St. Jude Hospital de Niños en Memphis como director de la División de trasplante de médula ósea. (es)
  • Malcolm K. Brenner (born August 4, 1951, in the UK) is a British clinical scientist working mostly in the field of gene therapy and immunotherapy applied to malignancy. In 2016, Dr. Brenner was elected to the National Academy of Medicine, part of the National Academies of Sciences, Engineering, and Medicine. The move in 1994 reflected his growing interest in the genetic-modification of T-cells for cancer therapy, cancer vaccines and monoclonal antibodies. (en)
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  • مالكوم برينر (بالإنجليزية: Malcolm Brenner)‏ هو عالم مناعة بريطاني، ولد في 4 أغسطس 1951. (ar)
  • Malcolm K. Brenner (born August 4, 1951, in the UK) is a British clinical scientist working mostly in the field of gene therapy and immunotherapy applied to malignancy. In 2016, Dr. Brenner was elected to the National Academy of Medicine, part of the National Academies of Sciences, Engineering, and Medicine. He was educated at Forest School, Walthamstow and Emmanuel College, Cambridge England. He received his medical degree and subsequent Ph.D. from Cambridge University, England. In the 1980s, he was a Lecturer in Hematology at Royal Free Hospital in London. In 1990, he left the UK to work in St. Jude Children's Research Hospital in Memphis as the director of the Bone Marrow Transplant Division. There, he conducted one of the first human gene therapy studies when he transduced bone marrow stem cells with a with the intention of marking them to study their survival and fate. This seminal study demonstrated that engrafted bone marrow stem cells contribute to long-term hematopoiesis and also that contaminating tumor cells in autografts can cause relapse. In 1994, he became the director of St. Jude's Cell and Gene Therapy Program. The move in 1994 reflected his growing interest in the genetic-modification of T-cells for cancer therapy, cancer vaccines and monoclonal antibodies. He was President of the International Society for Cellular Therapy and President of the American Society of Gene Therapy in 2002–2003. He was appointed Editor in Chief of the journal Molecular Therapy in 2009. Dr. Brenner was appointed Director of the Center for Cell and Gene Therapy. Dr. Brenner's is a full-time faculty member for the Center for Cell and Gene Therapy, Texas Children's Cancer Center and the Dan L. Duncan Cancer Center at Baylor College of Medicine, Houston, Texas. In 2017, Dr. Brenner was awarded the European Society of Gene and Cell Therapy Outstanding Achievement Award, and in 2020 the Career Achievement Award in Cell & Gene Therapy from the . (en)
  • Malcolm K. Brenner (4 de agosto de 1951 (71 años) es un científico clínico británico que trabaja mayoritariamente en el campo de terapia génica y la inmunoterapia aplicada a malignidad. Se educó en el Forest School London y luego en el Emmanuel College, de la Universidad de Cambridge. Recibió su grado médico y subsiguiente Ph.D. de la Universidad de Cambridge, Inglaterra. En los 1980s, fue un conferenciante en Hematología en Hospital Libre Real en Londres. En 1990, dejó el Reino Unido para trabajar en el St. Jude Hospital de Niños en Memphis como director de la División de trasplante de médula ósea. Allí condujo una de los primeros estudios de terapia génica humana cuándo sel transducieron células madre de médula ósea con un vector retroviral con la intención de marcarles y estudiar su supervivencia y destino. Este estudio seminal demostró que trasplantar células de médula ósea contribuyen mucho tiempo a una hematopoyesis y también que células contaminadas de tumor en autotrasplante pueden causar recaídas. En 1994, devino director del Programa St. Jude Terapia de células y genes. El movimiento en 1994 reflejó su interés de crecer en las modificaciones genéticas de linfocitos T para terapia de cáncer, vacunas de cáncer y anticuerpos monoclonales.​ Fue presidente de la Sociedad Internacional para Terapia Celular y presidente de la Sociedad americana de Terapia de Gen entre 2002 a 2003. Fue nombrado Editor Jefa de la revista Terapia Molecular en 2009. El Dr. Brenner fue nombrado Director del Centro para Célula y Terapia de[1] Gen. Es miembro de facultad de dedicación exclusiva para el Centro para Célula y Terapia de Gen, el centro de Cáncer de Niños de Texas y el Dan L. Centro de Cáncer del Duncan en Baylor Universidad de Medicina, Houston, Texas.​ (es)
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