Mark Stephen Wrighton (born June 11, 1949) is an American academic and chemist, and the current President of The George Washington University. In September 2021, Wrighton was named the Interim President of The George Washington University for an 18-month term and succeeded Thomas LeBlanc in January 2022. During his time at GWU, he will concurrently be on sabbatical from Washington University in St. Louis where he is the James and Mary Wertsch Distinguished University Professor and Chancellor Emeritus. Wrighton served as the 14th Chancellor of Washington University in St. Louis from 1995 to 2019.