Masonboro Island is a barrier island in New Hanover County, North Carolina, United States. The island, which is undeveloped and accessible only by boat, is a component of the North Carolina National Estuarine Research Reserve and a North Carolina State Natural Area. It lies south of Wrightsville Beach, separated by Masonboro Inlet, and north of Carolina Beach, separated by . The island is a destination for boating, surfing, and camping.