The Matapedia River (French: Rivière Matapédia) is a river in the Matapedia Valley in the province of Quebec, Canada. It runs on 65 kilometres (40 mi) from Matapedia Lake down to the village of Matapédia where it empties into the left bank of Restigouche River on the provincial border of New Brunswick. From the South side of Matapedia Lake and going to the South, the route 132 along the river goes on its entire length by the East bank.