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About: Maximal unique match     Goto   Sponge   NotDistinct   Permalink

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A maximal unique match or MUM, for short, is part of a key step in the multiple sequence alignment of genomes in computational biology. Identification of MUMs and other potential anchors, is the first step in larger alignment systems such as MUMmer. Anchors are the areas between two genomes where they are highly similar. To understand what a MUM is we each word in the acronym can be broken down individually. Match implies that the substring occurs in both sequences to be aligned. Unique means that the substring occurs only once in each sequence. Finally, maximal states that the substring is not part of another larger string that fulfills both prior requirements. The idea behind this, is that long sequences that match exactly and occur only once in each genome are almost certainly part