About: Mebutamate

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Mebutamate (Capla, Dormate) is an anxiolytic and sedative drug with antihypertensive effects of the carbamate class. It has effects comparable to those of barbiturates such as secobarbital, but is only around 1/3 the potency of secobarbital as a sedative. Side effects include dizziness and headaches. Other carbamates with the same mechanism of action and pharmacological properties include meprobamate, carisoprodol, felbamate, and tybamate.

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Drug yago:WikicatCarbamates yago:WikicatMolecularFormulas yago:Abstraction100002137 yago:Carbamate114792281 yago:Chemical114806838 yago:Communication100033020 yago:Compound114818238 yago:Formula106816935 yago:Material114580897 yago:Matter100020827 yago:Message106598915 yago:MolecularFormula106817173 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 drug yago:Salt115010703 yago:Statement106722453 yago:Substance100019613 umbel-rc:DrugProduct
rdfs:label	Mebutamate (en)
rdfs:comment	Mebutamate (Capla, Dormate) is an anxiolytic and sedative drug with antihypertensive effects of the carbamate class. It has effects comparable to those of barbiturates such as secobarbital, but is only around 1/3 the potency of secobarbital as a sedative. Side effects include dizziness and headaches. Other carbamates with the same mechanism of action and pharmacological properties include meprobamate, carisoprodol, felbamate, and tybamate. (en)
foaf:depiction
dcterms:subject	Carbamates GABAA receptor positive allosteric modulators Anxiolytics
Wikipage page ID	12718685 (xsd:integer)
Wikipage revision ID	1120068921 (xsd:integer)
Link from a Wikipage to another Wikipage	Carisoprodol Benzodiazepines Structural analog Pentabamate Carbamates GABAA receptor positive allosteric modulators Gabaergic Anxiolytic Barbiturate Tybamate Drug GABAA receptor Allosteric Analgesic Anxiolytics Felbamate Headaches Dizziness Meprobamate Secobarbital Sedative Lorbamate Antihypertensive
sameAs	Mebutamate Mebutamate Mebutamate Mebutamate Mebutamate Mebutamate
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:GABAAR_PAMs dbt:Reflist dbt:Short_description dbt:US_patent dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite dbt:Anxiolytics dbt:Sedative-stub
thumbnail	wiki-commons:Special:FilePath/Mebutamate.svg?width=300
ATC suffix	BC04 (en)
ATC prefix	N05 (en)
c	10 (xsd:integer)
CAS number	64 (xsd:integer)
ChEMBL	1200922 (xsd:integer)
ChemSpiderID	5919 (xsd:integer)
H	20 (xsd:integer)
IUPAC name	2 (xsd:integer)
KEGG	D01807 (en)
legal US	Schedule IV (en)
n	2 (xsd:integer)
O	4 (xsd:integer)
PubChem	6151 (xsd:integer)
SMILES	CCCCCOCN (en)
StdInChI	1 (xsd:integer)
StdInChIKey	LEROTMJVBFSIMP-UHFFFAOYSA-N (en)
UNII	5 (xsd:integer)
Verifiedfields	changed (en)
verifiedrevid	457633911 (xsd:integer)
Watchedfields	changed (en)
has abstract	Mebutamate (Capla, Dormate) is an anxiolytic and sedative drug with antihypertensive effects of the carbamate class. It has effects comparable to those of barbiturates such as secobarbital, but is only around 1/3 the potency of secobarbital as a sedative. Side effects include dizziness and headaches. Mebutamate is one of many GABAergic drugs which act via allosteric agonism of the GABAA receptor at the β-subreceptor similar to barbiturates. In contrast, benzodiazepines act at the α-subreceptor. As such, carbamates and barbiturates, possess analgesic properties while the benzodiazepine class of drugs are strictly psychoactive. Other carbamates with the same mechanism of action and pharmacological properties include meprobamate, carisoprodol, felbamate, and tybamate. (en)
gold:hypernym	Drug

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