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About: Membrane-bound transcription factor site-2 protease     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:ProteinMolecule, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: ThingBiomoleculeBiomoleculeProteinyago:Abstraction100002137yago:Activator114723079yago:Catalyst114723628yago:Chemical114806838yago:Compound114818238yago:Enzyme114732946yago:Macromolecule114944888yago:Material114580897yago:Matter100020827yago:Molecule114682133yago:OrganicCompound114727670yago:Part113809207yago:PhysicalEntity100001930yago:Protein114728724yago:Relation100031921proteinyago:Substance100019613yago:Thing100002452yago:Unit109465459umbel-rc:ProteinMolecule New Facet based on Instances of this Class

Membrane-bound transcription factor site-2 protease, also known as S2P endopeptidase or site-2 protease (S2P), is an enzyme (EC 3.4.24.85) encoded by the MBTPS2 gene which liberates the N-terminal fragment of sterol regulatory element-binding protein (SREBP) transcription factors from membranes. S2P cleaves the transmembrane domain of SREPB, making it a member of the class of intramembrane proteases. S2P catalyses the following chemical reaction This enzyme belongs to the peptidase family M50.