Mendota station is an Amtrak intercity train station at 783 Main Street, Mendota, Illinois, United States. The station was originally built on February 23, 1888, by the Chicago, Burlington and Quincy Railroad, as a replacement for the former Union Depot that was built in 1853 and burned down in 1885. It originally contained a hotel, restaurants and waiting rooms for passengers, and rooms for railroad employees. In 1942, much of the station was torn down, with little more than the waiting room and ticket office remaining intact.