About: Michele Pagano (biochemist)

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Michele Pagano is an Italian-American biochemist and cancer biologist best known for his work on cell cycle control and the ubiquitin-proteasome system. He is currently the chairman of the Department of Biochemistry and Molecular Pharmacology, and the Ellen and Gerald Ritter Professor of Oncology at the New York University School of Medicine. He is also an Investigator of the Howard Hughes Medical Institute. His laboratory has played a central role in elucidating the role of a family of enzymes, the cullin-RING ubiquitin ligases (CRLs), in mediating the proteolysis of key cellular regulators. In particular, his work has uncovered the molecular mechanisms by which CRLs control cell cycle progression, signal transduction pathways, and the DNA damage response. His work has also elucidated how

Attributes	Values
rdf:type	Thing
rdfs:label	Michele Pagano (biochemist) (en)
rdfs:comment	Michele Pagano is an Italian-American biochemist and cancer biologist best known for his work on cell cycle control and the ubiquitin-proteasome system. He is currently the chairman of the Department of Biochemistry and Molecular Pharmacology, and the Ellen and Gerald Ritter Professor of Oncology at the New York University School of Medicine. He is also an Investigator of the Howard Hughes Medical Institute. His laboratory has played a central role in elucidating the role of a family of enzymes, the cullin-RING ubiquitin ligases (CRLs), in mediating the proteolysis of key cellular regulators. In particular, his work has uncovered the molecular mechanisms by which CRLs control cell cycle progression, signal transduction pathways, and the DNA damage response. His work has also elucidated how (en)
dcterms:subject	Living people Year of birth missing (living people) American biochemists New York University Grossman School of Medicine faculty University of Naples Federico II alumni
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Link from a Wikipage to another Wikipage	Cancer Proteasome Sapienza University of Rome Boston Children's Hospital Howard Hughes Medical Institute List of Latin phrases (E) Cullin Cyclin-dependent kinase DNA repair DNA replication Ubiquitin ligase University of Illinois College of Medicine University of Naples Federico II University of Oxford University of Pennsylvania Living people Year of birth missing (living people) Columbia University Proteolysis Enzyme Patent Peer review Pharmaceutical industry Avram Hershko American biochemists New York University Grossman School of Medicine faculty Cyclin Estrogen receptor European Molecular Biology Laboratory Cell biology Cell cycle Cell signaling List of Nobel laureates Heidelberg Technical University of Munich ATM serine/threonine kinase University of Naples Federico II alumni Biochemist Biologist Signal transduction CDK inhibitor Metastasis National Institutes of Health National Institutes of Health MERIT Award New York University School of Medicine RING finger domain Ubiquitin University of Tokushima University of Verona NYU Malignant transformation National Institute of General Medical Sciences Molecular oncology
Link from a Wikipage to an external page	http://paganolab.org/assets/thescientist.pdf https://www.hhmi.org/scientists/michele-pagano https://faculty.mdanderson.org/profiles/giulio_draetta.html http://paganolab.org/patents.html http://paganolab.org https://www.ncbi.nlm.nih.gov/myncbi/michele.pagano.1/bibliography/public/ https://med.nyu.edu/departments-institutes/biochemistry-molecular-pharmacology/about-the-department https://med.nyu.edu/faculty/michele-pagano
sameAs	Michele Pagano (biochemist) Michele Pagano (biochemist) Michele Pagano (biochemist) Michele Pagano (biochemist) Michele Pagano (biochemist) Michele Pagano (biochemist)
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has abstract	Michele Pagano is an Italian-American biochemist and cancer biologist best known for his work on cell cycle control and the ubiquitin-proteasome system. He is currently the chairman of the Department of Biochemistry and Molecular Pharmacology, and the Ellen and Gerald Ritter Professor of Oncology at the New York University School of Medicine. He is also an Investigator of the Howard Hughes Medical Institute. His laboratory has played a central role in elucidating the role of a family of enzymes, the cullin-RING ubiquitin ligases (CRLs), in mediating the proteolysis of key cellular regulators. In particular, his work has uncovered the molecular mechanisms by which CRLs control cell cycle progression, signal transduction pathways, and the DNA damage response. His work has also elucidated how the dysregulation of CRLs contributes to malignant transformation and metastasis, uncovering new therapeutic strategies. (en)
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page length (characters) of wiki page	7227 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Michele_Pagano_(biochemist)
is Link from a Wikipage to another Wikipage of	FBXL2 FBXL3 List of deans and notable people at the NYU Grossman School of Medicine Michele Pagano CCNF Pagano (surname) Michele Pagano(biochemist) National Institutes of Health MERIT Award
is Wikipage redirect of	Michele Pagano(biochemist)
is Wikipage disambiguates of	Michele Pagano
is foaf:primaryTopic of	wikipedia-en:Michele_Pagano_(biochemist)

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