The Missouri Rhineland is a geographical area of Missouri that extends from west of St. Louis to slightly east of Jefferson City, located mostly in the Missouri River Valley on both sides of the river. Dutzow, the first permanent German settlement in Missouri, was founded in 1832 by Baron von Bock. The area is named after the Rhineland region in central Europe, a wine-growing area around the Rhine river, by German-Americans who noticed similarities in the two regions' soil and topography.