Mitra dynasty of Kosambi was centered on the city of Kosambi at the Vatsa region. Its capital Kosambi was among the most important trade centers in the ancient India. The dynasty also likely controlled territory in nearby regions such as Magadha. Common symbols in the coinage of the Mitra dynasty include the tree-in-railing and the Ujjain symbol. Bull is a common animal to appear on the coinage. The Mitra dynasty was ended when Samudragupta of the Gupta Empire annexed Kosambi in the middle of the 4th century CE.