Sir Neville Poole (died 1661) was an English politician who sat in the House of Commons variously between 1614 and 1648. He supported the Parliamentarian side in the English Civil War. Poole was the son of Sir Henry Poole of Cirencester and Oaksey and his wife Griselda Neville, daughter of Edward Nevill, 7th Baron Bergavenny. He entered Gray's Inn on 17 February 1611 and was knighted at Newmarket in January 1613. Poole was of Oaksey or Oxsey, Wiltshire, and was lord of the manor on South Cerney until he sold it to Sir Edward Atkyns.