A nick is a discontinuity in a double stranded DNA molecule where there is no phosphodiester bond between adjacent nucleotides of one strand typically through damage or enzyme action. Nicks allow DNA strands to untwist during replication, and are also thought to play a role in the DNA mismatch repair mechanisms that fix errors on both the leading and lagging daughter strands.
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| - Césure (génétique) (fr)
- ニック (DNA) (ja)
- Nick (DNA) (en)
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| - A nick is a discontinuity in a double stranded DNA molecule where there is no phosphodiester bond between adjacent nucleotides of one strand typically through damage or enzyme action. Nicks allow DNA strands to untwist during replication, and are also thought to play a role in the DNA mismatch repair mechanisms that fix errors on both the leading and lagging daughter strands. (en)
- Une césure, ou coupure simple brin, ou coupure haplotomique, ou cassure d'un brin, est la coupure d'une liaison phosphodiester entre deux nucléotides adjacents sur un des deux brins d'acide nucléique. Dans le génie génétique, ou lors de mutations, la césure est un mécanisme qui permet l'insertion d'une séquence de nucléotides, ou élément transposable ou transposon, dans le génome de la cellule hôte.
* Portail de la biologie cellulaire et moléculaire (fr)
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| - A nick is a discontinuity in a double stranded DNA molecule where there is no phosphodiester bond between adjacent nucleotides of one strand typically through damage or enzyme action. Nicks allow DNA strands to untwist during replication, and are also thought to play a role in the DNA mismatch repair mechanisms that fix errors on both the leading and lagging daughter strands. (en)
- Une césure, ou coupure simple brin, ou coupure haplotomique, ou cassure d'un brin, est la coupure d'une liaison phosphodiester entre deux nucléotides adjacents sur un des deux brins d'acide nucléique. Dans le génie génétique, ou lors de mutations, la césure est un mécanisme qui permet l'insertion d'une séquence de nucléotides, ou élément transposable ou transposon, dans le génome de la cellule hôte.
* Portail de la biologie cellulaire et moléculaire (fr)
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