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Noroxymorphone is an opioid which is both a metabolite of oxymorphone and oxycodone and is manufactured specifically as an intermediate in the production of narcotic antagonists such as naltrexone and others. It is a potent agonist of the μ-opioid receptor, but is poorly able to cross the blood-brain-barrier into the central nervous system, and for this reason, has only minimal analgesic activity.

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rdfs:label
  • Noroxymorphone (en)
rdfs:comment
  • Noroxymorphone is an opioid which is both a metabolite of oxymorphone and oxycodone and is manufactured specifically as an intermediate in the production of narcotic antagonists such as naltrexone and others. It is a potent agonist of the μ-opioid receptor, but is poorly able to cross the blood-brain-barrier into the central nervous system, and for this reason, has only minimal analgesic activity. (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/Noroxymorphone.svg
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Wikipage revision ID
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CAS number
ChemSpiderID
DrugBank
  • DBMET00424 (en)
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IUPAC name
legal US
  • Schedule II (en)
n
O
PubChem
routes of administration
  • intravenous, intramusucular, subcutaneous, oral, rectal, intranasal (en)
SMILES
  • Oc1ccc2C[C@H]3NCC[C@@]45[C@@H]CCC[C@@]35O (en)
StdInChI
StdInChIKey
  • HLMSIZPQBSYUNL-IPOQPSJVSA-N (en)
UNII
has abstract
  • Noroxymorphone is an opioid which is both a metabolite of oxymorphone and oxycodone and is manufactured specifically as an intermediate in the production of narcotic antagonists such as naltrexone and others. It is a potent agonist of the μ-opioid receptor, but is poorly able to cross the blood-brain-barrier into the central nervous system, and for this reason, has only minimal analgesic activity. In the United States, noroxymorphone is controlled as a Schedule II Narcotic controlled substance with an ACSCN of 9637 and in 2014 the DEA set annual aggregate manufacturing quotas of 17 500 kilogrammes for conversion and 1262.5 kg for sale. In other countries, it may be similarly controlled, controlled at a lower level, or regulated in another way. (en)
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page length (characters) of wiki page
CAS number
  • 33522-95-1
DrugBank
  • DBMET00424
FDA UNII code
  • 9NZ7111A9O
PubChem
  • 5497189
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