• Facets (new session)
• Description
• Metadata
• Settings
  • Rule: ActivityStreamsMapasEquivalentb3sb3sifpdbprdf-labelfacetshttp://dbpedia.org/resource/inference/rules/dbpedia#http://dbpedia.org/resource/inference/rules/opencyc#http://dbpedia.org/resource/inference/rules/umbel#http://dbpedia.org/resource/inference/rules/yago#http://dbpedia.org/schema/property_rules#http://www.ontologyportal.org/inference/rules/SUMO#http://www.ontologyportal.org/inference/rules/WordNet#http://www.w3.org/2002/07/owl#ldpoplwebskos-transurn:det:rdf:labelvirtrdf-labelvirtrdf-urlNone
    
  • Inverse Functional Properties: Disabled (fastest) Apply to subjects only Apply to objects only Apply to both subjects and objects
  • "Same As": Disabled (fastest) Apply to subjects only Apply to objects only Apply to both subjects and objects (recommended) Apply to subjects, objects and predicates (not recommended on big datasets) Apply to predicates only (special use cases only)

About: Omnigenic model     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Thing, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

The omnigenic model of the genetics of complex traits posits that human gene regulatory networks are so interconnected that thousands of individual genes contribute at least slightly to the phenotype through expression in relevant cells. Because it proposes that the genetic architecture of complex traits is affected by a large number of genes, it is similar to the infinitesimal model developed by Ronald Fisher. It also incorporates the concept of "universal pleiotropy", which states that genetic variation in one part of the genome can potentially have an indirect effect on any other trait. The model was first proposed by Boyle et al. in a 2017 paper in Cell. According to this model, a small number of "core genes" with biological relevance to a given trait, as well as their regulators and a