Ophir is an unincorporated area located in the Yukon-Koyukuk Census Area in the U.S. state of Alaska. It was named by miners after the wealthy land of Ophir mentioned in the Old Testament. The area was the site of a gold rush in 1906. Ophir reached a peak population of 122 in 1910. Ophir is now abandoned, but serves as a checkpoint in the Iditarod Trail Sled Dog Race. An airport with a single gravel runway exists at the village, built prior to 1949. It is currently in disuse and unmaintained.