The Palliser Region is an area in the southeast corner of the province of Alberta, Canada that has been delineated and is serviced by the Palliser Economic Partnership. It borders the Canadian province of Saskatchewan to the east, and the US state of Montana to the south. It covers an area of 43,504 km2 (16,797 sq mi) The total population of the area stood at 112,314 in 2009. The city of Medicine Hat, with a population of 61,097, is the area’s largest urban centre.