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Paramethadione (brand name Paradione) is an anticonvulsant in the oxazolidinedione class developed by the Illinois-based pharmaceutical company Abbott Laboratories (known as AbbVie since January 1, 2013 ), and approved by the Food and Drug Administration in 1949 for the treatment of absence seizures, also called partial seizures. In 1960, the yearly cost for 900 mg/day paramethadione was approximately $66, which would translate to $462 yearly in 2007 (with CPI inflation) if paramethadione was still sold.

AttributesValues
rdf:type
rdfs:label
  • Parametadiona (es)
  • Parametadione (it)
  • パラメタジオン (ja)
  • Paramethadione (en)
  • 甲乙双酮 (zh)
rdfs:comment
  • La parametadiona es un fármaco de la familia de las oxazolidindionas comercializado para crisis epilépticas.​ (es)
  • Paramethadione (brand name Paradione) is an anticonvulsant in the oxazolidinedione class developed by the Illinois-based pharmaceutical company Abbott Laboratories (known as AbbVie since January 1, 2013 ), and approved by the Food and Drug Administration in 1949 for the treatment of absence seizures, also called partial seizures. In 1960, the yearly cost for 900 mg/day paramethadione was approximately $66, which would translate to $462 yearly in 2007 (with CPI inflation) if paramethadione was still sold. (en)
  • パラメタジオン(Paramethadione)は、イリノイ州の製薬会社アボット・ラボラトリーズ(2013年1月1日以降はアッヴィ)が開発したオキサゾリジンジオン系の抗てんかん薬である。商標名はパラジオン(Paradione)。1949年に欠神発作の治療のためにアメリカ食品医薬品局(FDA)に承認された。 1960年時点で、1日分900mgの年間薬価は約66ドルであった。これは、2007年の物価にすると約462ドルである。 (ja)
  • Il parametadione è un farmaco anticonvulsivante che condivide le caratteristiche dei derivati dall'ossazolidina, e pertanto appartiene alla classe degli Ossazolidindioni. Il farmaco ha una maggiore attività sedativa rispetto al trimetadione.Contrariamente agli idantoinici ed ai barbiturici antiepilettici, il parametadione non modifica l'andamento dell'attacco epilettico in pazienti in terapia elettroconvulsiva. Il parametadione ha un effetto sedativo che può aumentare fino ad arrivare ad atassia quando si usano dosi eccessive. (it)
  • 甲乙双酮(Paramethadione)又称对甲双酮,是噁唑烷二酮类。此药物已知会造成。 (zh)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/Paramethadione.svg
dcterms:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
sameAs
dbp:wikiPageUsesTemplate
thumbnail
ATC suffix
  • AC01 (en)
ATC prefix
  • N03 (en)
c
CAS number
ChEMBL
ChemSpiderID
DrugBank
  • DB00617 (en)
H
IUPAC name
KEGG
  • D00495 (en)
n
O
pregnancy US
  • D (en)
PubChem
SMILES
  • O=C1NC (en)
StdInChI
StdInChIKey
  • VQASKUSHBVDKGU-UHFFFAOYSA-N (en)
UNII
  • Z615FRW64N (en)
verifiedrevid
Watchedfields
  • changed (en)
width
has abstract
  • La parametadiona es un fármaco de la familia de las oxazolidindionas comercializado para crisis epilépticas.​ (es)
  • Paramethadione (brand name Paradione) is an anticonvulsant in the oxazolidinedione class developed by the Illinois-based pharmaceutical company Abbott Laboratories (known as AbbVie since January 1, 2013 ), and approved by the Food and Drug Administration in 1949 for the treatment of absence seizures, also called partial seizures. In 1960, the yearly cost for 900 mg/day paramethadione was approximately $66, which would translate to $462 yearly in 2007 (with CPI inflation) if paramethadione was still sold. (en)
  • パラメタジオン(Paramethadione)は、イリノイ州の製薬会社アボット・ラボラトリーズ(2013年1月1日以降はアッヴィ)が開発したオキサゾリジンジオン系の抗てんかん薬である。商標名はパラジオン(Paradione)。1949年に欠神発作の治療のためにアメリカ食品医薬品局(FDA)に承認された。 1960年時点で、1日分900mgの年間薬価は約66ドルであった。これは、2007年の物価にすると約462ドルである。 (ja)
  • Il parametadione è un farmaco anticonvulsivante che condivide le caratteristiche dei derivati dall'ossazolidina, e pertanto appartiene alla classe degli Ossazolidindioni. Il farmaco ha una maggiore attività sedativa rispetto al trimetadione.Contrariamente agli idantoinici ed ai barbiturici antiepilettici, il parametadione non modifica l'andamento dell'attacco epilettico in pazienti in terapia elettroconvulsiva. Il parametadione ha un effetto sedativo che può aumentare fino ad arrivare ad atassia quando si usano dosi eccessive. (it)
  • 甲乙双酮(Paramethadione)又称对甲双酮,是噁唑烷二酮类。此药物已知会造成。 (zh)
chirality
IUPHAR ligand
protein bound
  • Not significant (en)
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