Pennsylvania Route 150 (PA 150) is a 41.1-mile-long (66.1 km) highway in Central Pennsylvania. Its southern terminus is at PA 26 in Dale Summit, Pennsylvania near State College, at the location of the Nittany Mall. Its northern terminus is at U.S. Route 220 (US 220) in Avis. Since the construction of Interstate 99 (I-99) in the area north of State College, the major use the southernmost portion of PA 150 is to connect traffic from the expressway to downtown State College and Pennsylvania State University (via a section of PA 26).