Pennsylvania Route 44 (PA 44) is a 149.24 mi (240.18 km)-long state highway in the U.S. state of Pennsylvania. The route, which is signed north-south, is designated from Interstate 80 (I-80) and PA 42 in Buckhorn northwest to the New York state line near New York State Route 417 (NY 417) in Ceres Township. Commissioned in 1927 by the Pennsylvania Department of Highways, PA 44 originally ran from the New York state line to Jersey Shore. Today, the highway is a scenic route from Columbia County to Potter County.