Pequea is an unincorporated community located in Martic Township in Lancaster County, Pennsylvania. It is where Route 324 ends at the Susquehanna River 12 miles south of Lancaster. The Pequea Creek empties into the river in Pequea, which is pronounced "Peckway." The ZIP code is 17565. Pequea has a hot-summer humid continental climate (Dfa) and average monthly temperatures range from 31.0° F in January to 75.4° F in July. The hardiness zone is 7a.