Plunketts Creek is an approximately 6.2-mile-long (10 km) tributary of Loyalsock Creek in Lycoming and Sullivan counties in the U.S. state of Pennsylvania. Two unincorporated villages and a hamlet are on the creek, and its watershed drains 23.6 square miles (61 km2) in parts of five townships. The creek is a part of the Chesapeake Bay drainage basin via Loyalsock Creek and the West Branch Susquehanna and Susquehanna Rivers.