About: Ponesimod

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Ponesimod, sold under the brand name Ponvory, is a medication for the treatment of multiple sclerosis (MS). The most common side effects include upper respiratory tract infection, hepatic transaminase elevation, and hypertension. Ponesimod was approved for medical use in the United States in March 2021 and in the European Union in June 2021.

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Drug drug
rdfs:label	Ponesimod (de) Ponésimod (fr) Ponesimod (en)
rdfs:comment	Ponesimod ist ein Arzneistoff aus der Gruppe der Immunmodulatoren, der zur oralen Behandlung der multiplen Sklerose (MS) eingesetzt wird. (de) Le ponésimod est un modulateur des récepteurs à la sphingosine-1-phosphate de type 1 (S1PR1) et est en cours de test dans la sclérose en plaques et le psoriasis. (fr) Ponesimod, sold under the brand name Ponvory, is a medication for the treatment of multiple sclerosis (MS). The most common side effects include upper respiratory tract infection, hepatic transaminase elevation, and hypertension. Ponesimod was approved for medical use in the United States in March 2021 and in the European Union in June 2021. (en)
foaf:depiction
dcterms:subject	Multiple sclerosis Immunosuppressants 2-Tolyl compounds Thiazolidines
Wikipage page ID	44262798 (xsd:integer)
Wikipage revision ID	1115708226 (xsd:integer)
Link from a Wikipage to another Wikipage	Bradycardia Oral administration Multiple sclerosis Lesions Lymph node Magnetic resonance imaging Committee for Medicinal Products for Human Use Multiple sclerosis Sphingosine-1-phosphate receptor Immunosuppressants Dyspnoea European Medicines Agency Fingolimod 2-Tolyl compounds dbr:Teriflunomide Psoriasis Area and Severity Index Thiazolidines Placebo Medication Lymphocyte S1PR1 Phase II clinical trial QT prolongation Relapsing Liver enzymes
Link from a Wikipage to an external page	https://druginfo.nlm.nih.gov/drugportal/name/ponesimod
sameAs	Ponesimod Ponesimod Ponesimod Ponesimod Ponesimod Ponesimod
dbp:wikiPageUsesTemplate	dbt:Cite_web dbt:Infobox_drug dbt:Portal_bar dbt:Reflist dbt:Fdacite dbt:Drugs.com dbt:Immunosuppressants dbt:Demyelinating_diseases_of_CNS dbt:Lysophospholipid_signaling
thumbnail	wiki-commons:Special:FilePath/Ponesimod.svg?width=300
ATC suffix	AA50 (en)
ATC prefix	L04 (en)
c	23 (xsd:integer)
CAS number	854107 (xsd:integer)
ChEMBL	1096146 (xsd:integer)
ChemSpiderID	9538103 (xsd:integer)
Cl	1 (xsd:integer)
DrugBank	DB12016 (en)
elimination half-life	-122400.0 (second)
excretion	Feces , urine (en)
H	25 (xsd:integer)
image	Ponesimod ball-and-stick model.png (en)
IUPAC name	-5 (xsd:integer)
KEGG	D11215 (en)
legal US	Rx-only (en)
metabolism	2 (xsd:integer)
n	2 (xsd:integer)
O	4 (xsd:integer)
PubChem	11363176 (xsd:integer)
routes of administration	Oral administration
s	1 (xsd:integer)
SMILES	CCC/N=C\1/NC3=CC=CC=C3C (en)
StdInChI	1 (xsd:integer)
StdInChIKey	LPAUOXUZGSBGDU-STDDISTJSA-N (en)
synonyms	ACT-128800 (en)
tradename	Ponvory (en)
UNII	5 (xsd:integer)
width	190 (xsd:integer)
has abstract	Ponesimod ist ein Arzneistoff aus der Gruppe der Immunmodulatoren, der zur oralen Behandlung der multiplen Sklerose (MS) eingesetzt wird. (de) Le ponésimod est un modulateur des récepteurs à la sphingosine-1-phosphate de type 1 (S1PR1) et est en cours de test dans la sclérose en plaques et le psoriasis. (fr) Ponesimod, sold under the brand name Ponvory, is a medication for the treatment of multiple sclerosis (MS). The most common side effects include upper respiratory tract infection, hepatic transaminase elevation, and hypertension. Ponesimod was approved for medical use in the United States in March 2021 and in the European Union in June 2021. (en)
DailyMedID	Ponesimod (en)
legal AU	S4 (en)
legal CA	Rx-only (en)
legal EU	Rx-only (en)
pregnancy AU	D (en)
gold:hypernym	Drug
prov:wasDerivedFrom	wikipedia-en:Ponesimod?oldid=1115708226&ns=0
page length (characters) of wiki page	13424 (xsd:nonNegativeInteger)

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