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Pumiliotoxin 251D is a toxic organic compound. It is found in the skin of poison frogs from the genera Dendrobates, Epipedobates, Minyobates, and Phyllobates and toads from the genus Melanophryniscus. Its name comes from the pumiliotoxin family (PTXs) and its molecular mass of 251 Daltons. When the toxin enters the bloodstream through cuts in the skin or by ingestion, it can cause hyperactivity, convulsions, cardiac arrest and ultimately death. It is especially toxic to arthropods (e.g. mosquitoes), even at low (naturally occurring) concentrations.

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  • Pumiliotoxin 251D (es)
  • Pumiliotoxin 251D (en)
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  • Pumiliotoxin 251D is a toxic organic compound. It is found in the skin of poison frogs from the genera Dendrobates, Epipedobates, Minyobates, and Phyllobates and toads from the genus Melanophryniscus. Its name comes from the pumiliotoxin family (PTXs) and its molecular mass of 251 Daltons. When the toxin enters the bloodstream through cuts in the skin or by ingestion, it can cause hyperactivity, convulsions, cardiac arrest and ultimately death. It is especially toxic to arthropods (e.g. mosquitoes), even at low (naturally occurring) concentrations. (en)
  • Pumiliotoxin 251D es una de las toxinas que se encuentran en la piel de las ranas venenosas de los géneros Dendrobates, Epipedobates, Minyobates, y Phyllobates​​ y los sapos del género Melanophryniscus.​​ No es fabricada por los anfibios, pero lo absorben a través de la dieta de rica en insectos.​​ Es extremadamente tóxico para los mosquitos.​ Pumiliotoxin 251D es una toxina potente con varios mecanismos de acción, incluyendo el bloqueo de los canales de sodio y de potasio en las células,​ y la inhibición de la .​​ (es)
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  • Pumiliotoxin251D.png (en)
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  • Pumiliotoxin 251D (en)
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