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About: R-spondin 4     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Thing, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

For chromosome 20, R-spondin 4 is a protein in humans that is encoded by the RSPO4 gene.This gene encodes a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenita. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2009].