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In molecular biology, a RING (short for Really Interesting New Gene) finger domain is a protein structural domain of zinc finger type which contains a C3HC4 amino acid motif which binds two zinc cations (seven cysteines and one histidine arranged non-consecutively). This protein domain contains 40 to 60 amino acids. Many proteins containing a RING finger play a key role in the ubiquitination pathway.

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rdf:type
rdfs:label
  • RING finger (cs)
  • Dedos de zinc RING (es)
  • RING finger domain (en)
  • RING (domena) (pl)
rdfs:comment
  • El dominio de dedo de zinc RING es un tipo de dedo de zinc que contiene un motivo caracterizado por la secuencia de aminoácidos Cys3HisCys4 capaz de unir cationes de zinc.​ Este dominio proteico contiene entre 40 y 60 aminoácidos. El acrónimo "RING" proviene de sus siglas en inglés "Really Interesting New Gene".​​​ (es)
  • In molecular biology, a RING (short for Really Interesting New Gene) finger domain is a protein structural domain of zinc finger type which contains a C3HC4 amino acid motif which binds two zinc cations (seven cysteines and one histidine arranged non-consecutively). This protein domain contains 40 to 60 amino acids. Many proteins containing a RING finger play a key role in the ubiquitination pathway. (en)
  • RING (ang. Really Interesting New Gene) – domena obecna w strukturze białek, złożona z palca cynkowego. Zawiera motyw składający się z siedmiu cystein i jednej histydyny (C3HC4), które koordynują dwa atomy cynku. Obecna u białek zaangażowanych w szlak ubikwitynacji ( - E3). Domenę odkryto po raz pierwszy w białku Ring1, odpowiedzialnym za monoubikwitynację histonu . Związek domeny RING z procesem ubikwitynacji zauważono w szeregu prac w 1999 roku. (pl)
  • RING finger (z angl. RING – Really Interesting New Gene) je proteinová doména podobná zinkovému prstu, obsahující Cys3HisCys4 (ale aminokyseliny nejsou zařazeny bezprostředně za sebou). Tento motiv je schopen vázat dva kationty zinku (Zn2+). Rozmístění důležitých cysteinů a histidinů je možné znázornit takto: CysX2CysX9–27CysXHisX2CysX2CysX6–17CysX2Cys. Má tuto konzervovanou strukturu: (cs)
name
  • Zinc finger, C3HC4 type (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/1chc_animated.gif
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