About: RNA silencing suppressor p19

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RNA silencing suppressor p19 (also known as Tombusvirus P19 core protein and 19 kDa symptom severity modulator) is a protein expressed from the ORF4 gene in the genome of tombusviruses. These viruses are positive-sense single-stranded RNA viruses that infect plant cells, in which RNA silencing forms a widespread and robust antiviral defense system. The p19 protein serves as a counter-defense strategy, specifically binding the 19- to 21-nucleotide double-stranded RNAs that function as small interfering RNA (siRNA) in the RNA silencing system. By sequestering siRNA, p19 suppresses RNA silencing and promotes viral proliferation. The p19 protein is considered a significant virulence factor and a component of an evolutionary arms race between plants and their pathogens.

Attributes	Values
rdf:type	Thing Biomolecule Biomolecule Protein protein
rdfs:label	RNA silencing suppressor p19 (en)
rdfs:comment	RNA silencing suppressor p19 (also known as Tombusvirus P19 core protein and 19 kDa symptom severity modulator) is a protein expressed from the ORF4 gene in the genome of tombusviruses. These viruses are positive-sense single-stranded RNA viruses that infect plant cells, in which RNA silencing forms a widespread and robust antiviral defense system. The p19 protein serves as a counter-defense strategy, specifically binding the 19- to 21-nucleotide double-stranded RNAs that function as small interfering RNA (siRNA) in the RNA silencing system. By sequestering siRNA, p19 suppresses RNA silencing and promotes viral proliferation. The p19 protein is considered a significant virulence factor and a component of an evolutionary arms race between plants and their pathogens. (en)
name	RNA silencing suppressor p19 (en)
foaf:depiction
dcterms:subject	Viral nonstructural proteins
Wikipage page ID	52500756 (xsd:integer)
Wikipage revision ID	1032089947 (xsd:integer)
Link from a Wikipage to another Wikipage	MicroRNA Mutation Nucleotide Beta sheet RNA interference Genome Open reading frame RNA silencing Gene Convergent evolution Tomato bushy stunt virus Protein crystallography Alpha helices Pathogen Viral nonstructural proteins Dicer Protein complex Dimer (chemistry) Reading frame Protein RNA RNA-induced silencing complex Argonaute Model organism C-terminus Positive-sense single-stranded RNA virus Carnation Italian ringspot virus Virus Small interfering RNA Plant cell Plant virus Evolutionary arms race N-terminus Molecular biology Virulence factor Non-coding RNA Tombusvirus Type species Protein fold Kilodalton Double-stranded RNA Repressor (genetics) Short interfering RNA Homodimer Overprinted gene dbr:DCL4 dbr:MiR-168 dbr:Movement_protein_p22
sameAs	RNA silencing suppressor p19 RNA silencing suppressor p19
dbp:wikiPageUsesTemplate	dbt:Infobox_protein_family dbt:Reflist dbt:Short_description dbt:Use_dmy_dates dbt:PDB dbt:Viral_proteins
thumbnail	wiki-commons:Special:FilePath/1R9F_tombusvirus_p19_dimer.png?width=300
caption	The protein dimer formed by two p19 molecules. Each monomer is colored from N-terminus to C-terminus to illustrate the end-to-end orientation of the dimer. The dotted gray line in the center highlights the dimer interface. From . (en)
InterPro	IPR004905 (en)
Pfam	PF03220 (en)
symbol	Tombus_p19 (en)
has abstract	RNA silencing suppressor p19 (also known as Tombusvirus P19 core protein and 19 kDa symptom severity modulator) is a protein expressed from the ORF4 gene in the genome of tombusviruses. These viruses are positive-sense single-stranded RNA viruses that infect plant cells, in which RNA silencing forms a widespread and robust antiviral defense system. The p19 protein serves as a counter-defense strategy, specifically binding the 19- to 21-nucleotide double-stranded RNAs that function as small interfering RNA (siRNA) in the RNA silencing system. By sequestering siRNA, p19 suppresses RNA silencing and promotes viral proliferation. The p19 protein is considered a significant virulence factor and a component of an evolutionary arms race between plants and their pathogens. (en)
prov:wasDerivedFrom	wikipedia-en:RNA_silencing_suppressor_p19?oldid=1032089947&ns=0
page length (characters) of wiki page	11022 (xsd:nonNegativeInteger)
Symbol	Tombus_p19
foaf:isPrimaryTopicOf	wikipedia-en:RNA_silencing_suppressor_p19
is Link from a Wikipage to another Wikipage of	Overlapping gene Tomato bushy stunt virus Onion yellow dwarf virus P19 Tombusvirus P19 core protein 19 kDa symptom severity modulator
is Wikipage redirect of	Tombusvirus P19 core protein 19 kDa symptom severity modulator
is foaf:primaryTopic of	wikipedia-en:RNA_silencing_suppressor_p19

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